Search results for "Iron Deficiency Anemia"

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Oral high-dose sucrosomial iron vs intravenous iron in sideropenic anemia patients intolerant/refractory to iron sulfate: a multicentric randomized s…

2020

AbstractIron deficiency anemia is among the most frequent causes of disability. Intravenous iron is the quickest way to correct iron deficiency, bypassing the bottleneck of iron intestinal absorption, the only true mechanism of iron balance regulation in human body. Intravenous iron administration is suggested in patients who are refractory/intolerant to oral iron sulfate. However, the intravenous way of iron administration requires several precautions; as the in-hospital administration requires a resuscitation service, as imposed in Europe by the European Medicine Agency, it is very expensive and negatively affects patient’s perceived quality of life. A new oral iron formulation, Sucrosomi…

AdultMalemedicine.medical_specialtyResuscitationIntravenous sodium ferrigluconateAnemiaCost-Benefit AnalysisHigh dosesAdministration OralHigh dose030204 cardiovascular system & hematologyGastroenterologyFerric CompoundsIntestinal absorption03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRefractoryInternal medicineOral Sucrosomial ironMedicineHumans030212 general & internal medicineFerrous CompoundsProspective StudiesAgedAged 80 and overHematologyAnemia Iron-Deficiencybusiness.industryHematologyGeneral MedicineIron deficiencyMiddle Agedmedicine.diseaseIron sulfatechemistryIron-deficiency anemiaIron deficiency anemiaHematinicsAdministration IntravenousFemaleOriginal ArticleRefractoriness/intolerance to oral iron sulfatebusiness
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Performance of a Predictive Model for Long-Term Hemoglobin Response to Darbepoetin and Iron Administration in a Large Cohort of Hemodialysis Patients

2016

International audience; Anemia management, based on erythropoiesis stimulating agents (ESA) and iron supplementation, has become an increasingly challenging problem in hemodialysis patients. Maintaining hemodialysis patients within narrow hemoglobin targets, preventing cycling outside target, and reducing ESA dosing to prevent adverse outcomes requires considerable attention from caregivers. Anticipation of the long-term response (i.e. at 3 months) to the ESA/iron therapy would be of fundamental importance for planning a successful treatment strategy. To this end, we developed a predictive model designed to support decision-making regarding anemia management in hemodialysis (HD) patients tr…

MalePediatricsBlood transfusionDarbepoetin alfaPhysiologymedicine.medical_treatment030232 urology & nephrologylcsh:Medicine030204 cardiovascular system & hematologyFerric CompoundsBiochemistryGlucaric AcidHemoglobinsMathematical and Statistical Techniques0302 clinical medicineMedicine and Health SciencesDarbepoetin alfaErythropoiesislcsh:ScienceFerric Oxide SaccharatedMultidisciplinaryPharmaceuticsDisease ManagementAnemia[SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/HematologyHematologyMiddle Aged3. Good healthNephrologyInjections IntravenousPhysical SciencesFemaleHemodialysisStatistics (Mathematics)Research Articlemedicine.drugComputer and Information Sciencesmedicine.medical_specialtyAnemiaResearch and Analysis Methods03 medical and health sciencesDose Prediction MethodsRenal DialysisArtificial IntelligenceMedical DialysismedicineHumansHemoglobinDosingStatistical MethodsIron Deficiency AnemiaIntensive care medicineArtificial Neural NetworksAgedRetrospective StudiesComputational NeuroscienceModels Statisticalbusiness.industrylcsh:RBiology and Life SciencesComputational BiologyProteinsRetrospective cohort studymedicine.diseaseIron-deficiency anemiaHematinicsKidney Failure ChronicCognitive Sciencelcsh:QNeural Networks ComputerHemoglobinPhysiological ProcessesbusinessMathematicsNeuroscienceForecasting
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